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Since Amyloidosis is an under-recognized disease, many times patients will be very sick by the time the correct diagnosis is made. It is not uncommon that a person with amyloidosis will need a heart, or kidney, or liver transplant in addition to a bone marrow transplant. Some patients may need more than one organ transplant.
We have one of the few clinics in the United States that offers multi-organ transplants to our patients with AL amyloidosis. We have a group of dedicated physicians, nurses and other health-care professionals who provide complete care to our patients.
Learn about one person's story and experience with amyloidosis.
There are several major types of this disease.
Immunoglobulin type-AL (L for light chain) which comes from abnormal cells in the bone marrow which form the miss-shaped proteins. This is the most common in the United States causing 5-13 new cases per million people per year. This can be treated with a bone marrow transplant or medical treatment.
Inflammation type-AA (A for associated with inflammation) which comes from miss-shaped proteins which originate from the liver. This is the most common type world-wide. Diseases like rheumatoid arthritis,
tuberculosis and familial Mediterranean fever can cause AA. This can be treated by treating the associated
disease that is causing the AA.
Hereditary-ATTR which runs in families as an autosomal dominant trait and is caused by an abnormal liver
protein. This can be treated by a liver transplant.
ABeta2Miroglobulin-dialysis associated which is seen in patients on long-term dialysis. This can be treated with a kidney transplant.