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Clinical Trials

Clinical Trials at The Methodist Hospital Research Institute

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NEUROSTIMULATION
Study Status: Active/Enrolling
Investigator: Torre, Guillermo
Study Coordinator: Khalil, Nashwa
Phone: (713) 441-2788
Summary:The purpose of this study is to study the use of neurostimulation in chronic advanced refractory heart failure. The study is determine if it is safe to use neurostimulation in patients with chronic a...(read more)
Other

ZA-203 Extension - Treatment of Hypogonadism (Low Testosterone)
Study Status: Active/Enrolling
Investigator: Mobley, David
Study Coordinator: Tambourides, Minna
Phone: 832-279-9469
Summary:The purpose of this study is to determine the continued effects of Androxal on morning testosterone and reproductive status in men with secondary hypogonadism who have completed protocol ZA-203. Men w...(read more)

Blood and Lymph Conditions
Active and enrolling clinical trials for Blood and Lymph Conditions are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Embolism and Thrombosis

Ovation
Study Status: Active/Enrolling
Investigator: Lumsden, Alan
Study Coordinator: Josey, Jennifer
Phone: 713-441-4628
Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more)

VM202
Study Status: Active/Enrolling
Investigator: Davies, Mark
Study Coordinator: Bass, Anastasia
Phone: 713-441-6539
Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more)
Hematologic Cancers

ENDEAVOR Carfilzomib and Dexamethasone Versus Velcade and Dexamethasone for Relapsed Multiple Myeloma Patients
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This Phase 3 study is a multicenter, open-label, randomized trial in patients with multiple myeloma whose disease has relapsed after at least 1 but not more than 3 prior therapeutic regimens. Patients...(read more)
Lymphoma

C14012: Alisertib or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This is a phase 3, randomized, 2-arm, open-label, international trial evaluating alisertib compared with single-agent treatment, as selected by the investigator from the offered options of pralatrexat...(read more)

MLN8237 in Relapsed or Refractory Aggressive B-Cell Lymphoma - C14011
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Woodard, Karen
Phone: 713-441-4332
Summary:This is a single-arm, open-label, multicenter, dose escalation, phase 1-2 study of alisertib (MLN8237) administered in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)/transf...(read more)

Cancers and Other Neoplasms
Active and enrolling clinical trials for Cancers and Other Neoplasms are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Brain and Central Nervous System Cancers

NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)

RTOG 0913
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as temozolomid...(read more)

RTOG 0929
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: ABT-888 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide. work in different ways to stop the growt...(read more)
Brain Cancers

NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)
Breast Cancers

BP22572 T-DM1 in Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This open-label, multi-center study will assess the safety and tolerability of adding trastuzumab emtansine (T-DM1) to docetaxel in patients with locally advanced or metastatic HER2-positive breast ca...(read more)

CAT Trial
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The major purpose of this research study is to better understand how therapy works on different patients. This study is being offered to patients with a diagnosis of advanced or metastatic breast canc...(read more)

Denosumab - Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Boone, Toniva
Phone: 7134410686
Summary:Purpose: This randomized phase 3 trial is studying the effect of denosumab to see if it can prevent disease recurrence in the bone or in any other part of the body, when it is given as adjuvant therap...(read more)

ECOG 2108
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:RATIONALE: Early surgery may have fewer side effects and improve recovery. Palliative surgery or radiation therapy may help patients with advanced breast cancer live more comfortably. It is not yet kn...(read more)

Ganetespib STA-9090 for Metastatic HER2 Positive or Triple Negative Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The purpose of this study is to determine if ganetespib (STA-9090) is effective in the treatment of patients with HER2+ or triple negative breast cancer who have not received prior systemic treatment ...(read more)

ICE Trial
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:Ixabepilone and capecitabine combination has demonstrated to be an active regimen in patients with metastatic breast cancer (MBC) after failing an anthracycline and a taxane regimen. Cetuximab is acti...(read more)

M12-895 Abbott Phase II
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The Study Evaluating Efficacy And Tolerability of Veliparib in Combination with Temozolomide or Veliparib/Placebo in Combination with Carboplatin and Paclitaxel in Subjects with Breast Cancer Gene (BR...(read more)

MEDI573 in Metastatic Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:This is a Phase 1b/2, multicenter, open-label study to evaluate the safety, tolerability, antitumor activity, and pharmacology of MEDI-573 in combination with an AI in adult subjects with HR+, HER2-ne...(read more)

Neoadjuvant Gene Expression Profile
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Boone, Toniva
Phone: 7134410686
Summary:This phase II trial is studying how well hormone therapy or chemotherapy before surgery based on gene expression analysis works in treating patients with breast cancer(read more)

NSABP B43
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or...(read more)

NSABP B47
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination ch...(read more)

NSABP DMP1
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:This clinical trial studies factors influencing decision-making about the use of chemoprevention in women at increased risk for breast cancer.(read more)

PROMIS registry of mammaprint in breast cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:This is a prospective registry study that will assess the impact of MammaPrint on chemotherapy + endocrine versus endocrine alone treatment decisions in patients with an Oncotype Intermediate Score.(read more)

S0812 Vitamin D in High Risk Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Cholecalciferol may prevent breast cancer in premenopausal women. PURPOSE: This randomized phase II trial is studying how well cholecalciferol works in preventing breast cancer in premenop...(read more)

S0927 Omega-3 for the Control of AI Induced Musculoskeletal Pain
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: An omega-3 fatty acid-enriched nutritional supplement may help improve muscle and bone pain and stiffness caused by hormone therapy in patients with breast cancer. PURPOSE: This randomized...(read more)

SWOG 1007
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy, using tamoxifen citrate, may fight breast cancer by blocking the use of estrogen by the tumor cells. Aromatase inhibit...(read more)

TDM4884g TDM1 for HER2 positive Locally Advanced or Metastatic Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:This is a multicenter, open-label, single-arm, expanded access study designed to provide T-DM1 to patients with HER2-positive locally advanced or metastatic breast cancer and to evaluate the safety an...(read more)

Trial of Active Immunotherapy With Globo H-KLH (OPT-822) in Metastatic Breast Cancer Subjects
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The purpose of this study is to compare active immunotherapy (OPT-822/OPT-821) with PBS in combination with low dose cyclophosphamide, in post-treated metastatic breast cancer subjects with stable dis...(read more)

Triple Negative RAD 001
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:RATIONALE: Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everol...(read more)
Hematologic Cancers

ENDEAVOR Carfilzomib and Dexamethasone Versus Velcade and Dexamethasone for Relapsed Multiple Myeloma Patients
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This Phase 3 study is a multicenter, open-label, randomized trial in patients with multiple myeloma whose disease has relapsed after at least 1 but not more than 3 prior therapeutic regimens. Patients...(read more)
Liver Cancers

IV GC33 in Patients with Advanced or Metastatic HCC
Study Status: Active/Enrolling
Investigator: Monsour, Howard
Study Coordinator: Dorman, Susan
Phone: 713-441-6316
Summary:This randomized, placebo-controlled, multicenter study will evaluate the efficacy and safety of RO5137382 (GC33) in previously treated patients with unresectable advanced or metastatic hepatocellular ...(read more)
Lymphoma

C14012: Alisertib or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This is a phase 3, randomized, 2-arm, open-label, international trial evaluating alisertib compared with single-agent treatment, as selected by the investigator from the offered options of pralatrexat...(read more)

MLN8237 in Relapsed or Refractory Aggressive B-Cell Lymphoma - C14011
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Woodard, Karen
Phone: 713-441-4332
Summary:This is a single-arm, open-label, multicenter, dose escalation, phase 1-2 study of alisertib (MLN8237) administered in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)/transf...(read more)
Prostate Cancers

LUTS Pilot - VESI-11E02
Study Status: Active/Enrolling
Investigator: Boone, Timothy
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:A single center, pilot trial with combination therapy of tamsulosin and solifenacin in 20 men with symptomatic lower urinary tract symptoms (LUTS). Subjects will be evaluated at baseline, 1, 2, and 3 ...(read more)

Vesicare to Improve Urinary Continence after Robotic Assisted Radical Prostatectomy
Study Status: Active/Enrolling
Investigator: Mobley, David
Study Coordinator: Tambourides, Minna
Phone: 832-279-9469
Summary:The purpose of this study is to assess the efficacy and safety of 12 weeks of treatment of VESIcare® versus placebo in subjects who are incontinent after Robotic Assisted Radical Prostatectomy. This ...(read more)
Urinary Tract Cancers

SWOG - S0931 - EVEREST - Renal Cancer
Study Status: Active/Enrolling
Investigator: Lehane, Daniel
Study Coordinator: Bieniemy, Dana
Phone: 713-441-0629
Summary:RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor. PURPOSE: This phase III trial is studying evero...(read more)

Digestive System Diseases
Active and enrolling clinical trials for Digestive System Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Diabetes Mellitus

EXAMINE
Study Status: Active/Enrolling
Investigator: Hamilton, Dale
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more)

EXSCEL
Study Status: Active/Enrolling
Investigator: Wyne, Kathleen
Study Coordinator: Coverdale, Catrina
Phone: 713-441-3927
Summary:This study will compare the impact of including exenatide once weekly as part of usual care vs. usual care without exenatide on major cardiovascular outcomes as measured by the primary cardiovascular ...(read more)
Liver Transplant

Terlipressin for Hepatorenal Syndrome
Study Status: Active/Enrolling
Investigator: Monsour, Howard
Study Coordinator: Dorman, Susan
Phone: 713-441-6316
Summary:This study is designed to evaluate the efficacy and safety of intravenous Lucassin® (terlipressin) versus placebo for the treatment of type 1 hepatorenal syndrome (HRS) in subjects receiving standard ...(read more)

Diseases and Abnormalities at or before Birth
Active and enrolling clinical trials for Diseases and Abnormalities at or before Birth are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Heart Defects

AC-058B201 Echocardiographic Ancillary Study
Study Status: Active/Enrolling
Investigator: Nagueh, Sherif
Study Coordinator: Frias, Maria
Phone: 713-441-2849
Summary:Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor ...(read more)

Corevalve Extreme Risks Patients
Study Status: Active/Enrolling
Investigator: Kleiman, Neal
Study Coordinator: Green, LaShawna
Phone: (713) 441-6548
Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more)

CoreValve High Risk Surgical Patients
Study Status: Active/Enrolling
Investigator: Reardon, Michael
Study Coordinator: Green, LaShawna
Phone: (713) 441-6548
Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more)

Gland and Hormone Related Diseases
Active and enrolling clinical trials for Gland and Hormone Related Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Breast Cancers

BP22572 T-DM1 in Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This open-label, multi-center study will assess the safety and tolerability of adding trastuzumab emtansine (T-DM1) to docetaxel in patients with locally advanced or metastatic HER2-positive breast ca...(read more)

CAT Trial
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The major purpose of this research study is to better understand how therapy works on different patients. This study is being offered to patients with a diagnosis of advanced or metastatic breast canc...(read more)

Denosumab - Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Boone, Toniva
Phone: 7134410686
Summary:Purpose: This randomized phase 3 trial is studying the effect of denosumab to see if it can prevent disease recurrence in the bone or in any other part of the body, when it is given as adjuvant therap...(read more)

ECOG 2108
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:RATIONALE: Early surgery may have fewer side effects and improve recovery. Palliative surgery or radiation therapy may help patients with advanced breast cancer live more comfortably. It is not yet kn...(read more)

Ganetespib STA-9090 for Metastatic HER2 Positive or Triple Negative Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The purpose of this study is to determine if ganetespib (STA-9090) is effective in the treatment of patients with HER2+ or triple negative breast cancer who have not received prior systemic treatment ...(read more)

ICE Trial
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:Ixabepilone and capecitabine combination has demonstrated to be an active regimen in patients with metastatic breast cancer (MBC) after failing an anthracycline and a taxane regimen. Cetuximab is acti...(read more)

M12-895 Abbott Phase II
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The Study Evaluating Efficacy And Tolerability of Veliparib in Combination with Temozolomide or Veliparib/Placebo in Combination with Carboplatin and Paclitaxel in Subjects with Breast Cancer Gene (BR...(read more)

MEDI573 in Metastatic Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:This is a Phase 1b/2, multicenter, open-label study to evaluate the safety, tolerability, antitumor activity, and pharmacology of MEDI-573 in combination with an AI in adult subjects with HR+, HER2-ne...(read more)

Neoadjuvant Gene Expression Profile
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Boone, Toniva
Phone: 7134410686
Summary:This phase II trial is studying how well hormone therapy or chemotherapy before surgery based on gene expression analysis works in treating patients with breast cancer(read more)

NSABP B43
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or...(read more)

NSABP B47
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination ch...(read more)

NSABP DMP1
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:This clinical trial studies factors influencing decision-making about the use of chemoprevention in women at increased risk for breast cancer.(read more)

PROMIS registry of mammaprint in breast cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:This is a prospective registry study that will assess the impact of MammaPrint on chemotherapy + endocrine versus endocrine alone treatment decisions in patients with an Oncotype Intermediate Score.(read more)

S0812 Vitamin D in High Risk Breast Cancer
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Cholecalciferol may prevent breast cancer in premenopausal women. PURPOSE: This randomized phase II trial is studying how well cholecalciferol works in preventing breast cancer in premenop...(read more)

S0927 Omega-3 for the Control of AI Induced Musculoskeletal Pain
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: An omega-3 fatty acid-enriched nutritional supplement may help improve muscle and bone pain and stiffness caused by hormone therapy in patients with breast cancer. PURPOSE: This randomized...(read more)

SWOG 1007
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Sinclair, Toni
Phone: (713) 441-1159
Summary:RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy, using tamoxifen citrate, may fight breast cancer by blocking the use of estrogen by the tumor cells. Aromatase inhibit...(read more)

TDM4884g TDM1 for HER2 positive Locally Advanced or Metastatic Breast Cancer
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:This is a multicenter, open-label, single-arm, expanded access study designed to provide T-DM1 to patients with HER2-positive locally advanced or metastatic breast cancer and to evaluate the safety an...(read more)

Trial of Active Immunotherapy With Globo H-KLH (OPT-822) in Metastatic Breast Cancer Subjects
Study Status: Active/Enrolling
Investigator: Rodriguez, Angel
Study Coordinator: Salazar, Maria
Phone: 713-441-6011
Summary:The purpose of this study is to compare active immunotherapy (OPT-822/OPT-821) with PBS in combination with low dose cyclophosphamide, in post-treated metastatic breast cancer subjects with stable dis...(read more)

Triple Negative RAD 001
Study Status: Active/Enrolling
Investigator: Chang, Jenny
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:RATIONALE: Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everol...(read more)
Diabetes Mellitus

EXAMINE
Study Status: Active/Enrolling
Investigator: Hamilton, Dale
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more)

EXSCEL
Study Status: Active/Enrolling
Investigator: Wyne, Kathleen
Study Coordinator: Coverdale, Catrina
Phone: 713-441-3927
Summary:This study will compare the impact of including exenatide once weekly as part of usual care vs. usual care without exenatide on major cardiovascular outcomes as measured by the primary cardiovascular ...(read more)
Liver Transplant

Terlipressin for Hepatorenal Syndrome
Study Status: Active/Enrolling
Investigator: Monsour, Howard
Study Coordinator: Dorman, Susan
Phone: 713-441-6316
Summary:This study is designed to evaluate the efficacy and safety of intravenous Lucassin® (terlipressin) versus placebo for the treatment of type 1 hepatorenal syndrome (HRS) in subjects receiving standard ...(read more)
Osteoporosis

P-15 Bone Putty in ACDF
Study Status: Active/Enrolling
Investigator: Baskin, David
Study Coordinator: Resendez, Darla
Phone: 713-441-3803
Summary:The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented ante...(read more)
Prostate Cancers

LUTS Pilot - VESI-11E02
Study Status: Active/Enrolling
Investigator: Boone, Timothy
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:A single center, pilot trial with combination therapy of tamsulosin and solifenacin in 20 men with symptomatic lower urinary tract symptoms (LUTS). Subjects will be evaluated at baseline, 1, 2, and 3 ...(read more)

Vesicare to Improve Urinary Continence after Robotic Assisted Radical Prostatectomy
Study Status: Active/Enrolling
Investigator: Mobley, David
Study Coordinator: Tambourides, Minna
Phone: 832-279-9469
Summary:The purpose of this study is to assess the efficacy and safety of 12 weeks of treatment of VESIcare® versus placebo in subjects who are incontinent after Robotic Assisted Radical Prostatectomy. This ...(read more)

Heart and Blood Diseases
Active and enrolling clinical trials for Heart and Blood Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Arrythmias

Hansen System with ThermoCool® for Patients with PAF
Study Status: Active/Enrolling
Investigator: Valderrabano, Miguel
Study Coordinator: Tindel, Melinda
Phone: 713-441-3248
Summary:The purpose of this study is to assess the safety and performance of the Hansen Medical Sensei Robotic System and Artisan Catheter when used to robotically manipulate the Biosense ThermoCool ablation ...(read more)

IRASE AF
Study Status: Active/Enrolling
Investigator: Rami, Tapan
Study Coordinator: Tindel, Melinda
Phone: 713-441-3248
Summary:The purpose of this study is to test the safety and effectiveness of an Irrigated Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation.(read more)
Atherosclerosis and Arteriosclerosis

Ovation
Study Status: Active/Enrolling
Investigator: Lumsden, Alan
Study Coordinator: Josey, Jennifer
Phone: 713-441-4628
Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more)

VM202
Study Status: Active/Enrolling
Investigator: Davies, Mark
Study Coordinator: Bass, Anastasia
Phone: 713-441-6539
Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more)
Coronary Artery Disease

EXAMINE
Study Status: Active/Enrolling
Investigator: Hamilton, Dale
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more)

EXCEL
Study Status: Active/Enrolling
Investigator: Shah, Alpesh
Study Coordinator: Sosa, Lenis
Phone: 713-441-3245
Summary:To establish the safety and efficacy of the XIENCE PRIME or XIENCE V Everolimus Eluting Coronary Stent System (EECSS) in subjects with unprotected left main coronary artery disease by comparing to cor...(read more)

EXPERT CTO
Study Status: Active/Enrolling
Investigator: Shah, Alpesh
Study Coordinator: Sosa, Lenis
Phone: 713-441-3245
Summary:A prospective, multi-center, single-arm study to establish the safety and effectiveness of the XIENCE V® Everolimus Eluting Coronary Stent, XIENCE nano™ Everolimus Eluting Coronary Stent, HT PROGRESS ...(read more)

IRASE AF
Study Status: Active/Enrolling
Investigator: Rami, Tapan
Study Coordinator: Tindel, Melinda
Phone: 713-441-3248
Summary:The purpose of this study is to test the safety and effectiveness of an Irrigated Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation.(read more)
Embolism and Thrombosis

Ovation
Study Status: Active/Enrolling
Investigator: Lumsden, Alan
Study Coordinator: Josey, Jennifer
Phone: 713-441-4628
Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more)

VM202
Study Status: Active/Enrolling
Investigator: Davies, Mark
Study Coordinator: Bass, Anastasia
Phone: 713-441-6539
Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more)
Heart Defects

AC-058B201 Echocardiographic Ancillary Study
Study Status: Active/Enrolling
Investigator: Nagueh, Sherif
Study Coordinator: Frias, Maria
Phone: 713-441-2849
Summary:Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor ...(read more)

Corevalve Extreme Risks Patients
Study Status: Active/Enrolling
Investigator: Kleiman, Neal
Study Coordinator: Green, LaShawna
Phone: (713) 441-6548
Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more)

CoreValve High Risk Surgical Patients
Study Status: Active/Enrolling
Investigator: Reardon, Michael
Study Coordinator: Green, LaShawna
Phone: (713) 441-6548
Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more)
Heart Failure

Freedom Driver
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more)

SynCardia TAH-t PM Surveillance Study
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more)
Heart Transplant

Freedom Driver
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more)

SynCardia TAH-t PM Surveillance Study
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more)
Myocardial Ischemia

EXAMINE
Study Status: Active/Enrolling
Investigator: Hamilton, Dale
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more)

EXCEL
Study Status: Active/Enrolling
Investigator: Shah, Alpesh
Study Coordinator: Sosa, Lenis
Phone: 713-441-3245
Summary:To establish the safety and efficacy of the XIENCE PRIME or XIENCE V Everolimus Eluting Coronary Stent System (EECSS) in subjects with unprotected left main coronary artery disease by comparing to cor...(read more)

EXPERT CTO
Study Status: Active/Enrolling
Investigator: Shah, Alpesh
Study Coordinator: Sosa, Lenis
Phone: 713-441-3245
Summary:A prospective, multi-center, single-arm study to establish the safety and effectiveness of the XIENCE V® Everolimus Eluting Coronary Stent, XIENCE nano™ Everolimus Eluting Coronary Stent, HT PROGRESS ...(read more)
Stroke

AMERICA
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:Ten study centers from US are anticipated to participate for this evaluation. Published literature on coils with electrolytic, thermal or hydraulic detachment will serve as the basis for control compa...(read more)

GTN
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:The current proposal describes a post-market, clinical registry of HydroSoft, aimed at gaining robust clinical data in a large set of patients to better define the advantages, and potentially, the dis...(read more)

Immune System Diseases
Active and enrolling clinical trials for Immune System Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Lymphoma

C14012: Alisertib or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Froehlich, Amber
Phone: 713-441-0685
Summary:This is a phase 3, randomized, 2-arm, open-label, international trial evaluating alisertib compared with single-agent treatment, as selected by the investigator from the offered options of pralatrexat...(read more)

MLN8237 in Relapsed or Refractory Aggressive B-Cell Lymphoma - C14011
Study Status: Active/Enrolling
Investigator: Iyer, Swaminathan
Study Coordinator: Woodard, Karen
Phone: 713-441-4332
Summary:This is a single-arm, open-label, multicenter, dose escalation, phase 1-2 study of alisertib (MLN8237) administered in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)/transf...(read more)

Muscle, Bone, and Cartilage Diseases & Disorders
Active and enrolling clinical trials for Muscle, Bone, and Cartilage Diseases & Disorders are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Bone Diseases

P-15 Bone Putty in ACDF
Study Status: Active/Enrolling
Investigator: Baskin, David
Study Coordinator: Resendez, Darla
Phone: 713-441-3803
Summary:The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented ante...(read more)
Osteoporosis

P-15 Bone Putty in ACDF
Study Status: Active/Enrolling
Investigator: Baskin, David
Study Coordinator: Resendez, Darla
Phone: 713-441-3803
Summary:The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented ante...(read more)

Nervous System Diseases & Disorders
Active and enrolling clinical trials for Nervous System Diseases & Disorders are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Amyotrophic Lateral Sclerosis (ALS)

Pyrimethamine in FALS
Study Status: Active/Enrolling
Investigator: Appel, Stanley
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.(read more)

Validation of ALS Biomarkers
Study Status: Active/Enrolling
Investigator: Pleitez, Milvia
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The purpose of this study is to collect 650 blood and 300 cerebrospinal fluid (CSF) samples from people with amyotrophic lateral sclerosis (ALS), pure lower or upper motor neuron diseases, as well as ...(read more)
Brain and Central Nervous System Cancers

NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)

RTOG 0913
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as temozolomid...(read more)

RTOG 0929
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: ABT-888 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide. work in different ways to stop the growt...(read more)
Brain Cancers

NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)
Neurodegenerative Diseases

AC-058B201 Echocardiographic Ancillary Study
Study Status: Active/Enrolling
Investigator: Nagueh, Sherif
Study Coordinator: Frias, Maria
Phone: 713-441-2849
Summary:Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor ...(read more)

Pyrimethamine in FALS
Study Status: Active/Enrolling
Investigator: Appel, Stanley
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.(read more)

Validation of ALS Biomarkers
Study Status: Active/Enrolling
Investigator: Pleitez, Milvia
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The purpose of this study is to collect 650 blood and 300 cerebrospinal fluid (CSF) samples from people with amyotrophic lateral sclerosis (ALS), pure lower or upper motor neuron diseases, as well as ...(read more)
Stroke

AMERICA
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:Ten study centers from US are anticipated to participate for this evaluation. Published literature on coils with electrolytic, thermal or hydraulic detachment will serve as the basis for control compa...(read more)

GTN
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:The current proposal describes a post-market, clinical registry of HydroSoft, aimed at gaining robust clinical data in a large set of patients to better define the advantages, and potentially, the dis...(read more)

Nutritional and Metabolic Conditions & Diseases
Active and enrolling clinical trials for Nutritional and Metabolic Conditions & Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Atherosclerosis and Arteriosclerosis

Ovation
Study Status: Active/Enrolling
Investigator: Lumsden, Alan
Study Coordinator: Josey, Jennifer
Phone: 713-441-4628
Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more)

VM202
Study Status: Active/Enrolling
Investigator: Davies, Mark
Study Coordinator: Bass, Anastasia
Phone: 713-441-6539
Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more)
Diabetes Mellitus

EXAMINE
Study Status: Active/Enrolling
Investigator: Hamilton, Dale
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more)

EXSCEL
Study Status: Active/Enrolling
Investigator: Wyne, Kathleen
Study Coordinator: Coverdale, Catrina
Phone: 713-441-3927
Summary:This study will compare the impact of including exenatide once weekly as part of usual care vs. usual care without exenatide on major cardiovascular outcomes as measured by the primary cardiovascular ...(read more)

Symptoms and General Pathology
Active and enrolling clinical trials for Symptoms and General Pathology are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Headache

PREMIUM Trial
Study Status: Active/Enrolling
Investigator: Volpi, John
Study Coordinator: Tindel, Melinda
Phone: 713-441-3248
Summary:The Purpose of this study is to evaluate the impact of percutaneous closure of a patent foramen ovale (a hole in the heart), using the AMPLATZER PFO Occluder, on the incidence of migraine headaches.(read more)

Transplant Trials
Active and enrolling clinical trials for Transplant Trials are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Graft Failure

LCP-Tacro 3002
Study Status: Active/Enrolling
Investigator: Knight, Richard
Study Coordinator: Jones, Sherri
Phone: 713-441-6396
Summary:This study will evaluate the efficacy and safety of LCP-Tacro (tacrolimus) Tablets administered once-a-day compared to Prograf (tacrolimus) Capsules twice-a-day as immunosuppression for the prevention...(read more)
Heart Transplant

Freedom Driver
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more)

SynCardia TAH-t PM Surveillance Study
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more)
Kidney Transplant

LCP-Tacro 3002
Study Status: Active/Enrolling
Investigator: Knight, Richard
Study Coordinator: Jones, Sherri
Phone: 713-441-6396
Summary:This study will evaluate the efficacy and safety of LCP-Tacro (tacrolimus) Tablets administered once-a-day compared to Prograf (tacrolimus) Capsules twice-a-day as immunosuppression for the prevention...(read more)
Liver Transplant

Terlipressin for Hepatorenal Syndrome
Study Status: Active/Enrolling
Investigator: Monsour, Howard
Study Coordinator: Dorman, Susan
Phone: 713-441-6316
Summary:This study is designed to evaluate the efficacy and safety of intravenous Lucassin® (terlipressin) versus placebo for the treatment of type 1 hepatorenal syndrome (HRS) in subjects receiving standard ...(read more)
Medical Devices

Fistula Plug for Use in Anal Fistula Repair
Study Status: Active/Enrolling
Investigator: Bailey, H. Randolph
Study Coordinator: Cleere, Darrel
Phone: 713-441-6232
Summary:The primary purpose of this prospective, multicenter, observational, single arm study is to substantiate efficacy of the GORE® BIO-A® Fistula Plug when used as a soft tissue reinforcement of anal fist...(read more)

Urinary Tract, Sexual Organs, and Pregnancy Conditions
Active and enrolling clinical trials for Urinary Tract, Sexual Organs, and Pregnancy Conditions are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Kidney Transplant

LCP-Tacro 3002
Study Status: Active/Enrolling
Investigator: Knight, Richard
Study Coordinator: Jones, Sherri
Phone: 713-441-6396
Summary:This study will evaluate the efficacy and safety of LCP-Tacro (tacrolimus) Tablets administered once-a-day compared to Prograf (tacrolimus) Capsules twice-a-day as immunosuppression for the prevention...(read more)
Prostate Cancers

LUTS Pilot - VESI-11E02
Study Status: Active/Enrolling
Investigator: Boone, Timothy
Study Coordinator: Whipple, Melissa
Phone: 713-441-3247
Summary:A single center, pilot trial with combination therapy of tamsulosin and solifenacin in 20 men with symptomatic lower urinary tract symptoms (LUTS). Subjects will be evaluated at baseline, 1, 2, and 3 ...(read more)

Vesicare to Improve Urinary Continence after Robotic Assisted Radical Prostatectomy
Study Status: Active/Enrolling
Investigator: Mobley, David
Study Coordinator: Tambourides, Minna
Phone: 832-279-9469
Summary:The purpose of this study is to assess the efficacy and safety of 12 weeks of treatment of VESIcare® versus placebo in subjects who are incontinent after Robotic Assisted Radical Prostatectomy. This ...(read more)
Urinary Tract Cancers

SWOG - S0931 - EVEREST - Renal Cancer
Study Status: Active/Enrolling
Investigator: Lehane, Daniel
Study Coordinator: Bieniemy, Dana
Phone: 713-441-0629
Summary:RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor. PURPOSE: This phase III trial is studying evero...(read more)