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| Home > The Methodist Hospital Research Institute > Clinical Trials |
Clinical Trials at The Methodist Hospital Research Institute |
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Heart and Blood Diseases |
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| Active and enrolling clinical trials for Heart and Blood Diseases are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health. | |
| For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250. | |
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Arrythmias Hansen System with ThermoCool® for Patients with PAF Study Status: Active/Enrolling Investigator: Valderrabano, Miguel Study Coordinator: Tindel, Melinda Phone: 713-441-3248 Summary:The purpose of this study is to assess the safety and performance of the Hansen Medical Sensei Robotic System and Artisan Catheter when used to robotically manipulate the Biosense ThermoCool ablation ...(read more) IRASE AF Study Status: Active/Enrolling Investigator: Rami, Tapan Study Coordinator: Tindel, Melinda Phone: 713-441-3248 Summary:The purpose of this study is to test the safety and effectiveness of an Irrigated Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation.(read more) |
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Atherosclerosis and Arteriosclerosis Ovation Study Status: Active/Enrolling Investigator: Lumsden, Alan Study Coordinator: Josey, Jennifer Phone: 713-441-4628 Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more) VM202 Study Status: Active/Enrolling Investigator: Davies, Mark Study Coordinator: Bass, Anastasia Phone: 713-441-6539 Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more) |
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Coronary Artery Disease EXAMINE Study Status: Active/Enrolling Investigator: Hamilton, Dale Study Coordinator: Whipple, Melissa Phone: 713-441-3247 Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more) EXCEL Study Status: Active/Enrolling Investigator: Shah, Alpesh Study Coordinator: Sosa, Lenis Phone: 713-441-3245 Summary:To establish the safety and efficacy of the XIENCE PRIME or XIENCE V Everolimus Eluting Coronary Stent System (EECSS) in subjects with unprotected left main coronary artery disease by comparing to cor...(read more) EXPERT CTO Study Status: Active/Enrolling Investigator: Shah, Alpesh Study Coordinator: Sosa, Lenis Phone: 713-441-3245 Summary:A prospective, multi-center, single-arm study to establish the safety and effectiveness of the XIENCE V® Everolimus Eluting Coronary Stent, XIENCE nano™ Everolimus Eluting Coronary Stent, HT PROGRESS ...(read more) IRASE AF Study Status: Active/Enrolling Investigator: Rami, Tapan Study Coordinator: Tindel, Melinda Phone: 713-441-3248 Summary:The purpose of this study is to test the safety and effectiveness of an Irrigated Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation.(read more) |
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Embolism and Thrombosis Ovation Study Status: Active/Enrolling Investigator: Lumsden, Alan Study Coordinator: Josey, Jennifer Phone: 713-441-4628 Summary:The primary objectives of this study are to determine whether the TriVascular AAA Stent Graft is a safe and effective method of treating abdominal aortic aneurysms (AAA's) in those patients considered...(read more) VM202 Study Status: Active/Enrolling Investigator: Davies, Mark Study Coordinator: Bass, Anastasia Phone: 713-441-6539 Summary:The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia(read more) |
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Heart Defects AC-058B201 Echocardiographic Ancillary Study Study Status: Active/Enrolling Investigator: Nagueh, Sherif Study Coordinator: Frias, Maria Phone: 713-441-2849 Summary:Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor ...(read more) Corevalve Extreme Risks Patients Study Status: Active/Enrolling Investigator: Kleiman, Neal Study Coordinator: Green, LaShawna Phone: (713) 441-6548 Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more) CoreValve High Risk Surgical Patients Study Status: Active/Enrolling Investigator: Reardon, Michael Study Coordinator: Green, LaShawna Phone: (713) 441-6548 Summary:The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for...(read more) |
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Heart Failure Freedom Driver Study Status: Active/Enrolling Investigator: Bruckner, Brian Study Coordinator: Bunge, Raquel Phone: 713-441-6509 Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more) SynCardia TAH-t PM Surveillance Study Study Status: Active/Enrolling Investigator: Bruckner, Brian Study Coordinator: Bunge, Raquel Phone: 713-441-6509 Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more) |
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Heart Transplant Freedom Driver Study Status: Active/Enrolling Investigator: Bruckner, Brian Study Coordinator: Bunge, Raquel Phone: 713-441-6509 Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more) SynCardia TAH-t PM Surveillance Study Study Status: Active/Enrolling Investigator: Bruckner, Brian Study Coordinator: Bunge, Raquel Phone: 713-441-6509 Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more) |
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Myocardial Ischemia EXAMINE Study Status: Active/Enrolling Investigator: Hamilton, Dale Study Coordinator: Whipple, Melissa Phone: 713-441-3247 Summary:The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin, once daily (QD), compared with placebo, in addition to standard of care, in subjects with type 2 diabetes mellitus a...(read more) EXCEL Study Status: Active/Enrolling Investigator: Shah, Alpesh Study Coordinator: Sosa, Lenis Phone: 713-441-3245 Summary:To establish the safety and efficacy of the XIENCE PRIME or XIENCE V Everolimus Eluting Coronary Stent System (EECSS) in subjects with unprotected left main coronary artery disease by comparing to cor...(read more) EXPERT CTO Study Status: Active/Enrolling Investigator: Shah, Alpesh Study Coordinator: Sosa, Lenis Phone: 713-441-3245 Summary:A prospective, multi-center, single-arm study to establish the safety and effectiveness of the XIENCE V® Everolimus Eluting Coronary Stent, XIENCE nano™ Everolimus Eluting Coronary Stent, HT PROGRESS ...(read more) |
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Stroke AMERICA Study Status: Active/Enrolling Investigator: Diaz, Orlando Study Coordinator: Bautista, Marilyn Phone: 713-441-1409 Summary:Ten study centers from US are anticipated to participate for this evaluation. Published literature on coils with electrolytic, thermal or hydraulic detachment will serve as the basis for control compa...(read more) GTN Study Status: Active/Enrolling Investigator: Diaz, Orlando Study Coordinator: Bautista, Marilyn Phone: 713-441-1409 Summary:The current proposal describes a post-market, clinical registry of HydroSoft, aimed at gaining robust clinical data in a large set of patients to better define the advantages, and potentially, the dis...(read more) |
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