Clinical Trials at The Methodist Hospital Research Institute |
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Nervous System Diseases & Disorders |
| Active and enrolling clinical trials for Nervous System Diseases & Disorders are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health. |
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| For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250. |
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Amyotrophic Lateral Sclerosis (ALS)
Pyrimethamine in FALS
Study Status: Active/Enrolling
Investigator: Appel, Stanley
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.(read more)
Validation of ALS Biomarkers
Study Status: Active/Enrolling
Investigator: Pleitez, Milvia
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The purpose of this study is to collect 650 blood and 300 cerebrospinal fluid (CSF) samples from people with amyotrophic lateral sclerosis (ALS), pure lower or upper motor neuron diseases, as well as ...(read more)
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Brain and Central Nervous System Cancers
NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)
RTOG 0913
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as temozolomid...(read more)
RTOG 0929
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:RATIONALE: ABT-888 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide. work in different ways to stop the growt...(read more)
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Brain Cancers
NovoCure EF-14
Study Status: Active/Enrolling
Investigator: New, Pamela
Study Coordinator: Harris, Kimbra
Phone: 713-441-3834
Summary:The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatm...(read more)
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Neurodegenerative Diseases
AC-058B201 Echocardiographic Ancillary Study
Study Status: Active/Enrolling
Investigator: Nagueh, Sherif
Study Coordinator: Frias, Maria
Phone: 713-441-2849
Summary:Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor ...(read more)
Pyrimethamine in FALS
Study Status: Active/Enrolling
Investigator: Appel, Stanley
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.(read more)
Validation of ALS Biomarkers
Study Status: Active/Enrolling
Investigator: Pleitez, Milvia
Study Coordinator: Halton, Sharon
Phone: 713-441-3420
Summary:The purpose of this study is to collect 650 blood and 300 cerebrospinal fluid (CSF) samples from people with amyotrophic lateral sclerosis (ALS), pure lower or upper motor neuron diseases, as well as ...(read more)
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Stroke
AMERICA
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:Ten study centers from US are anticipated to participate for this evaluation. Published literature on coils with electrolytic, thermal or hydraulic detachment will serve as the basis for control compa...(read more)
GTN
Study Status: Active/Enrolling
Investigator: Diaz, Orlando
Study Coordinator: Bautista, Marilyn
Phone: 713-441-1409
Summary:The current proposal describes a post-market, clinical registry of HydroSoft, aimed at gaining robust clinical data in a large set of patients to better define the advantages, and potentially, the dis...(read more)
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